Wednesday, May 19, 2010

Ranson's Criteria

Table 33-4 Ranson's
Prognostic Signs of Pancreatitis

Criteria for acute pancreatitis not due to gallstones 
At admissionDuring the initial 48 h
  Age >55 y  Hematocrit fall >10 points
  WBC >16,000/mm3
  BUN elevation >5 mg/dL
  Blood glucose >200 mg/dL  Serum calcium <8 mg/dL
  Serum LDH >350 IU/L  Arterial PO2 <60
mm Hg
  Serum AST >250 U/dL  Base deficit >4 mEq/L
     Estimated fluid sequestration >6 L
Criteria for acute gallstone pancreatitis 
At admissionDuring the initial 48 h
  Age >70 y  Hematocrit fall >10 points
  WBC >18,000/mm3
  BUN elevation >2 mg/dL
  Blood glucose >220 mg/dL  Serum calcium <8 mg/dL
  Serum LDH >400 IU/L  Base deficit >5 mEq/L
  Serum AST >250 U/dL  Estimated fluid sequestration >4 L


AST = aspartate
transaminase; BUN = blood urea nitrogen; LDH = lactate
dehydrogenase; PO2 = partial pressure
of oxygen; WBC = white blood cell count.

Source: Data from Ranson JHC: Etiological and prognostic factors
in human acute pancreatitis: A review. Am J Gastroenterol 77:633,
1982. From Macmillan Publishers Ltd. Ranson JH, Rifkind KM, Roses
DF, et al: Prognostic signs and the role of operative management
in acute pancreatitis. Surg Gynecol Obstet 139:69,
1974.

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