Treatment anaphylaxis

Epinephrine

Epinephrine 1:1000, 0.01 mg/kg to a maximum of 0.5 mg, should be injected intramuscularly, without delay. This dose may be repeated at intervals of 5–15 minutes as necessary for controlling symptoms and maintaining blood pressure. 

Antihistamines

CPM an H₁-blocker, 0.1 mg/kg IV q 6 hr.

Ranitidine, an H₂-blocker, 1 mg/kg up to 50 mg intravenously

Cimetidine, an H2-blocker, 4 mg/kg IV q 8-12 hr

Fluids

Treatment of persistent hypotension despite epinephrine requires restoration of intravascular volume by fluid replacement, initially with a crystalloid solution, 20–30 mL/kg in the first hour.

Bronchodilators

Nebulized ₂-agonists Salbutamol(Ventolin) (5mg/1ml)  dose 0.03-0.05 ml/kg/dose diluted in 2–3 mL saline

Corticosteroids

for prevent biphasic anaphylaxis. Intravenous methylprednisolone, 1 mg/kg, or hydrocortisone, 5 mg/kg, can be given every 6 hours.