Tuesday, June 15, 2010

Standard initial management in Heart failure

  • Supplemental Oxygen
  • Endotracheal intubation with mechanical ventilation is indicated if instability
  • Cardiac monitoring
  • pulse oximetry
  • 12-lead electrocardiogram
  • Intravenous access
  • Frequent vital sign assessments.
  • Chest radiography
  • Complete blood cell count
  • Electrolytes
  • BNP level
  • Cardiac markers
Acute Pulmonary Edema
  • Intravenous diuretics, diuresis can begin 10 to 15 min after intravenous furosemide. If urine output is inadequate in 20 to 30 min, the diuretic dose is increased and repeated.
  • Furosemide Dose  
              No prior use: 40 mg IVP
              If prior use: Double last 24-h usage (range, 80–180 mg)
              If no effect by 20–30 mins: re-double dose

Natriuretic Peptide Assay(BNP levels) in Heart Failure

These proteins are released by ventricular pressure or volume stimulus.
Age < 50    BNP level cut point = 450 pg/ml
Age 50-75  BNP level cut point = 900 pg/ml
Age >75     BNP level cut point = 1900 pg/ml


There are confounders to BNP as an HF test. BNP is increased in the elderly, women, those with cirrhosis or renal failure, possibly those on hormone replacement therapy, and probably those with pulmonary embolus and primary pulmonary hypertension. 

Precipitating Heart failure

  • Hypertension
  • Endocrine
  • Anemia
  • Rheumatic heart disease
  • Toxin
  • Failure to take meds
  • Arrhythmia
  • Infection
  • Lung (pulmonary embolism)
  • Electrolytes
  • Diet (excess Na+)